Everything you need to know about Loprin in Pakistan

loprin tablet uses

What is Loprin?

Loprin is an anti-inflammatory drug that acts by reducing the substances in your body that cause inflammation, pain, and fever. It also acts as an antiplatelet agent by inhibiting the clumping of platelets that cause blockage of the blood vessels. Therefore it is given prophylactically, and long-term as prevention of heart attacks and stroke as well.

Loprin tablet uses

Loprin is used to treat the following conditions.

  • Mild to moderate headache
  • Migraine
  • Sciatica
  • Lumbago
  • Rheumatic pain
  • Neuralgia
  • Rheumatic fever
  • Acute coronary syndrome
  • Kawasaki disease
  • Acute ischemic attack
  • Cerebrovascular and peripheral artery disease

How to take Loprin?

You must take Loprin with food as it may upset your stomach or cause gastric ulcers when taken on an empty stomach. Tell your doctor if you feel stomach pain or nausea, as it may be a sign of gastritis. Try to take it for the shortest possible time. Do not crush or chew the tablet.

Loprin dosage and strength

Loprin is available as enteric-coated tablets. It is available in the following dosage strengths;

  • 75mg, and 150mg.
  • Loprin dosage;
  • For the treatment of rheumatoid arthritis;
  • Initially, 3 grams/day PO in divided doses.
  • For the management of joint pain due to osteoarthritis;
  • 3 grams/day PO or less in divided doses.

Loprin side effects

The side effects of Loprin may include;

  • Abdominal pain
  • Vomit containing coffee grounds
  • Blood in stool
  • Constipation
  • Black stools
  • Acid reflux

Loprin formula

The main chemical component of Loprin is aspirin, also known as acetylsalicylic acid.

What are the alternatives to Loprin?

The alternatives to Loprin are;

  • Anaprin
  • Ascard
  • Disprin

How is Loprin classified?

Loprin is aspirin that belongs to a group of painkillers and anti-inflammatory drugs. It works by stopping the release of chemical mediators that cause pain, thrombosis, and inflammation.

What are the risks and warnings for Loprin?

Allergic to Aspirin

If you are allergic to Aspirin, do not take Loprin or any other medicine with the same generic name, as it can result in a life-threatening condition called anaphylactic shock. Anaphylactic shock is a rare but severe allergic reaction which if not treated at the right time can be life-threatening.

It shows the signs and symptoms such as hives, pale skin, labored breathing, itching, excessive salivation, feeling too warm, a weak and rapid pulse, nausea, vomiting, runny nose, sneezing, swollen lips and tongue, wheezing, dizziness, low blood pressure, and tingling hands, feet, mouth, or scalp.

Skin reaction

If you ever have had a skin reaction known as Steven Johnson syndrome upon Loprin intake, do not take it next time. Tell your healthcare provider your complete medical history.

Glucose 6 phosphate dehydrogenase deficiency

Patients who have a condition called glucose 6 phosphate dehydrogenase deficiency, must take Loprin with extreme caution as it can cause hemolysis.


People suffering from long-term malnutrition must take Loprin with caution.

Loprin in pregnancy

You should take Loprin during pregnancy only if your health care provider prescribes it. They may decide it based on the risk versus benefit ratio.

Otherwise, taking analgesics during pregnancy, especially during the second and third trimester, can be injurious to your baby’s health. Women of childbearing age should keep in mind to leave it as soon as they conceive. But before leaving it, you should consult with your healthcare provider. Do not leave it without the permission of your healthcare provider.


Mothers who are breastfeeding their child should take Loprin only on the advice of their healthcare provider as some of its concentration can be present in breast milk and affect your child’s health.


If a patient has lost a lot of fluid and is dehydrated, they should be given paracetamol IV with caution.

Gastric ulcers

People suffering from gastric ulcers and acidity must take Loprin with extreme caution because it inhibits the chemicals that protect the lining of your gastrointestinal tract.

Also, it can cause ulceration in your stomach lining when taken for the long term. Your doctor may prescribe a gastroprotection along with Loprin.

Anticoagulants or bleeding disorders

If you are taking anticoagulants for thinning of your blood, or you have any bleeding disorder, take Loprin only on the advice of a healthcare provider. It inhibits the chemicals responsible for making clotting factors, and anticoagulants also do that. When taken together, they can result in bleeding due to increased anticoagulant action.

Kidney disease

Patients suffering from kidney disease must take Loprin with caution because it can itself cause kidney impairment when taken for a long time.


Loprin can precipitate existing asthma. Therefore, take it with caution if you are asthmatic.

Interaction between Loprin and other medications

Loprin may interact with the following drugs. A drug interaction does not mean that you stop taking the medicine on your own. But you must tell your healthcare provider about it.

  • ACE inhibitors like captopril, fosinopril and enalapril, etc
  • Angiotensin receptor blockers like losartan, valsartan etc
  • Corticosteroids like prednisolone
  • Potassium supplements
  • Aspirin
  • Lithium
  • Blood thinners like clopidogrel, enoxaparin, warfarin, etc

To avoid drug interactions, you must give a complete history to the healthcare provider about other health conditions you have and what medicines you have been taking. At times, a dose adjustment can help prevent drug interaction.

Loprin tablet price in Pakistan

The price of Loprin tablet in Pakistan in the year 2022 is Rs.1.65 per tablet approximately.

Storage conditions

  • Keep the product out of the reach and sight of children.
  • Store it at room temperature.
  • Do not use it after the mentioned expiry date.
  • Protect it from direct heat and sunlight.

Do you need a prescription to buy Loprin?

For buying Loprin, you do not require to have the prescription signed by your doctor. You can buy it from any pharmacy nearby.

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